IN THE SPOTLIGHT

Tiragolumab Plus Atezolizumab and Chemotherapy in Extensive-Stage Small Cell Lung Cancer

Tiragolumab Plus Atezolizumab and Chemotherapy in Extensive-Stage Small Cell Lung Cancer

Small Cell SMASHERS Fireside Chat with Dr. Simon Heeke

Small Cell SMASHERS Fireside Chat with Dr. Simon Heeke

In May, we were joined by Simon Heeke, PhD, MD Anderson Cancer Center. Dr. Heeke discussed biomarker identification and their potential roles in patients impacted by SCLC.Moderated by Misty Shields, MD, PhD, Indiana University School of Medicine, and LUNGevity’s Ann Fish-Steagall, SVP of Patient Services and Health Care Delivery, this monthly virtual series highlights the latest discoveries and breakthroughs for SCLC.

Smart & Practical Tips From a Financial Navigator

Smart & Practical Tips From a Financial Navigator

This video is a recording from a LUNGevity virtual meetup. Each month, we host multiple virtual meetups for those impacted by lung cancer to meet and connect with others who understand them and what they’re going through.Periodically, we invite an expert to speak on a topic at the beginning of a meetup, with the second half dedicated to questions and conversation. Visit the online calendar to see our virtual meetups and other upcoming events.For this meetup, we welcomed Zarek Mena, OPN-CG,…

Epigenomic profiling of neuroendocrine lung cancers identifies a classical-neuroendocrine ASCL1/NKX2-1 subtype and a SOX11-associated differentiation axis linked to reduced immunogenicity

Epigenomic profiling of neuroendocrine lung cancers identifies a classical-neuroendocrine ASCL1/NKX2-1 subtype and a SOX11-associated differentiation axis linked to reduced immunogenicity

Outpatient Administration of Tarlatamab for Small Cell Lung Cancer: Real-World Experiences

Outpatient Administration of Tarlatamab for Small Cell Lung Cancer: Real-World Experiences

SN BioScience Inc. Initiates Global Phase 1b/2 Trial Of SNB 101 In Extensive Stage Small Cell Lung Cancer

SN BioScience Inc. Initiates Global Phase 1b/2 Trial Of SNB 101 In Extensive Stage Small Cell Lung Cancer

Brain Metastasis Still Remains a Major Unmet Need in Extensive-Stage Small Cell Lung Cancer

Brain Metastasis Still Remains a Major Unmet Need in Extensive-Stage Small Cell Lung Cancer

Real-world multi-institution analysis of tarlatamab in patients with small cell lung cancer

Real-world multi-institution analysis of tarlatamab in patients with small cell lung cancer

SN BioScience Initiates First Dosing in SNB-101 Clinical Trial for Lung Cancer

SN BioScience Initiates First Dosing in SNB-101 Clinical Trial for Lung Cancer

Watch Small Cell SMASHERS Live Sessions from HOPE Summit 2026

Watch Small Cell SMASHERS Live Sessions from HOPE Summit 2026

At HOPE Summit 2026—for the first time ever—we hosted Small Cell SMASHERS Live sessions with Misty Shields, MD, PhD, Indiana University School of Medicine. We recorded these sessions so everyone in the Small Cell Lung Cancer community can access the valuable information shared. Small Cell SMASHERS Live Recorded Sessions Blazing New Trails in SCLC: Exploring Genetics & Biology  Deep in the Heart of Research: Texas-Sized SCLC Advances  The New Frontier: FDA…

Watch HOPE Summit 2026 Videos

Watch HOPE Summit 2026 Videos

HOPE Summit 2026 was filled with old friends reuniting, new friends being made, and of course, plenty of inspirational and informative sessions designed to help people live well with lung cancer.For the second year in a row, select sessions were recorded so those who could not attend are still able to access the valuable information shared.HOPE Summit 2026 Recorded Sessions Keynote: Wagons Roll with Dr. Ross Camidge  Back in the Saddle: Reclaiming Strength and Living Well …

International Clinical Trial: A real-world study on the treatment of extensive-stage small cell lung cancer with toripalimab combined with chemotherapy at different intervals

International Clinical Trial: A real-world study on the treatment of extensive-stage small cell lung cancer with toripalimab combined with chemotherapy at different intervals

Small Cell SMASHERS Fireside Chat with Dr. Catherine Meador

Small Cell SMASHERS Fireside Chat with Dr. Catherine Meador

In April, we were joined by Catherine Meador, MD, PhD, assistant professor of medicine at Harvard Medical School. Dr. Meador discussed Transformed SCLC: Understanding Biology, Detection, and Identifying Novel Targets. Moderated by Misty Shields, MD, PhD, Indiana University School of Medicine, and LUNGevity’s Ann Fish-Steagall, RN, BSN, SVP of Patient Services and Health Care Delivery, the monthly Small Cell SMASHERS series highlights the latest discoveries and breakthroughs for SCLC.

Clinical Trial Access Isn’t Expanding. It’s Concentrating.

Clinical Trial Access Isn’t Expanding. It’s Concentrating.

Clinical trials show us whether a new treatment is safe and effective. They are also an important way for patients to access cutting-edge care. For trials to truly serve the lung cancer community, the people who enroll in the trials need to represent the populations who are diagnosed in everyday life.Recognizing these needs, federal agencies like the United States Food and Drug Administration (FDA) have been encouraging clinical trials to offer more locations across the US.The PlanThe intention…

Podcast: Why Community Matters in Lung Cancer Care

Podcast: Why Community Matters in Lung Cancer Care

Why does finding community matter in lung cancer care? In this episode, lung cancer survivor and advocate Jill Feldman shares her experience, from losing multiple family members to lung cancer to her own diagnosis, as well as her work building patient communities around the world. She discusses how connecting with others has shaped her journey and why community is important for support, information, and advocacy.Hosts Ann Steagall, RN, BSN, and Misty Shields, MD, PhD, explore with Jill how…

Podcast: Lung Cancer Diagnosis—What Happens Next

Podcast: Lung Cancer Diagnosis—What Happens Next

What happens after a lung cancer diagnosis? In this first episode of LUNGevity’s Lung Cancer Voices of Hope podcast, lung cancer survivor Lisa Bistline shares her experience, from initial scans and biopsies through multiple treatments, and the moment a later biopsy revealed a biomarker that led to a targeted therapy.Hosts Ann Steagall and Misty Shields, MD, PhD, then speak with Anne Chiang, MD, PhD, thoracic oncologist at Yale University, about what patients can expect at their first visit,…

Scalp Care, Shaving, and Head Coverings: Comfort Through Hair Loss

Scalp Care, Shaving, and Head Coverings: Comfort Through Hair Loss

This video is a recording from a LUNGevity virtual meetup. Each month, we host multiple virtual meetups for those impacted by lung cancer to meet and connect with others who understand them and what they’re going through.Periodically, we invite an expert to speak on a topic at the beginning of a meetup, with the second half dedicated to questions and conversation. Visit the online calendar to see our virtual meetups and other upcoming events.For this meetup, we welcomed Jenna Doyle Ruhl and…

Meet The “Mini-Organs” of Lung Cancer Research

Meet The “Mini-Organs” of Lung Cancer Research

Though many of us would like to deny it, our neighbors affect us. Their loud music disturbs our sleep. The scent of their dinner wafts through an open window. The sight of their new puppy brings a smile. We interact with our environment every moment of the day. And so do lung cancer cells.  A Brief HistoryTraditionally, we have studied tumor cells in isolation. We often study single cells in a petri dish, or under a microscope, to understand how they work. This has been very important and…

Explaining BiTE® Therapy

Explaining BiTE® Therapy

 A bi-specific T-cell engager (BiTE®) is a new type of engineered molecule used for the treatment of cancer. These molecules harness and activate T-cells, which are involved in the body’s immune response, to attack tumor cells. There is currently one FDA-approved BiTE® therapy treatment for targeting small cell lung cancer (SCLC).The video below was created to give you clear, easy-to-understand information about bi-specific T-cell engagers, so you can feel more informed and prepared as you…

Small Cell SMASHERS Fireside Chat with Dr. Laura Alder

Small Cell SMASHERS Fireside Chat with Dr. Laura Alder

In March, we were joined by Laura Alder, MD, assistant professor of medicine in the Division of Medical Oncology at Duke University Medical Center, to discuss the topic of managing brain metastases in SCLC.Moderated by Misty Shields, MD, PhD, Indiana University School of Medicine, and LUNGevity’s Ann Fish-Steagall, RN, BSN, SVP of Patient Services and Health Care Delivery, the monthly Small Cell SMASHERS series highlights the latest discoveries and breakthroughs for SCLC.

Progress in Cancer Care: What the Numbers Tell Us About Lung Cancer

Progress in Cancer Care: What the Numbers Tell Us About Lung Cancer

Every January, the American Cancer Society releases a Cancer Facts & Figures report. It provides a clear view of where we stand in addressing cancer. The 2026 report brings both encouraging news and a sobering reminder that our work is far from over.The Big Picture Shows Real ProgressLet’s start with the good news. We have made significant strides in cancer care over the past three decades. Since 1991, the cancer death rate has dropped by 34%. This translates to approximately 4.8 million…

Artificial Intelligence in Lung Cancer: Hope vs. Hype

Artificial Intelligence in Lung Cancer: Hope vs. Hype

Artificial intelligence (AI) is rapidly reshaping the future of cancer care, but such dramatic innovation also brings important questions.AI has evolved from early consumer tools (like autocorrect on phones, customer service chatbots, and personalized shopping recommendations) to advanced systems with the potential to revolutionize biomedical discovery and patient care. While there is tremendous excitement around AI, there is also a critical need to use it responsibly.Researchers are actively…

Small Cell SMASHERS Fireside Chat with Dr. Eric Singhi

Small Cell SMASHERS Fireside Chat with Dr. Eric Singhi

Eric Singhi, MD, assistant professor, University of Texas MD Anderson Cancer Center, joined us to discuss the role of community and support in people with small cell lung cancer.Moderated by Misty Shields, MD, PhD, IU Health, and LUNGevity’s Ann Fish-Steagall, RN, BSN, SVP of Patient Services and Health Care Delivery, the monthly Small Cell SMASHERS series highlights the latest discoveries and breakthroughs for SCLC.

Why Immunotherapy Isn’t Perfect & How Scientists Are Working to Fix It

Why Immunotherapy Isn’t Perfect & How Scientists Are Working to Fix It

The human immune system is an intricate web of checks and balances that usually excels at detecting and destroying foreign invaders, such as bacteria and viruses, while protecting healthy tissue. But sometimes, the checks and balances get confused and stop the immune system from doing what’s right—such as killing tumor cells.  Tumor cells are good at confusing the immune system because they originate from our healthy cells. They can often avoid detection by immune cells. Through several…

New Horizons in Immunotherapy: Lung Cancer Highlights from the 2025 SITC Meeting

New Horizons in Immunotherapy: Lung Cancer Highlights from the 2025 SITC Meeting

The Society for Immunotherapy of Cancer (SITC) celebrated their 40th anniversary at their annual meeting in National Harbor, Maryland from November 5-9, 2025. The meeting focused on multidisciplinary research aiming to leverage the immune system to improve outcomes for cancer patients, including  several exciting areas of growth in lung cancer-directed immunotherapy.Tumor Imaging is Growing More Powerful  Advanced imaging techniques are poised to change how we understand and treat…

The Future of Lung Cancer Starts Here

The Future of Lung Cancer Starts Here

For more than two decades, LUNGevity Foundation has been a leader in advancing lung cancer research. Since 2002, we have invested  $55+ million in more than 200 research projects, helping to build a robust pipeline of discoveries in early detection, treatment innovation, and health equity.Once again, LUNGevity is ready to open our annual grant cycle in 2026 with five research programs designed to address the most pressing challenges in lung cancer care. In addition, these grants ensure the…

Biggest News from Berlin: Research Highlights from ESMO

Biggest News from Berlin: Research Highlights from ESMO

Lung cancer research was in the spotlight at the European Society for Medical Oncology (ESMO) meeting held October 17-21, 2025, in Berlin, Germany. With approximately 30,000 attendees from over 100 countries, this meeting gathered an international audience of clinicians, researchers, patient advocates, and representatives from the healthcare industry to discuss cutting-edge cancer research and share practice-changing clinical trial data.  We saw data from studies that aim to build upon…

Small Cell SMASHERS Fireside Chat with Dr. Misty Shields

Small Cell SMASHERS Fireside Chat with Dr. Misty Shields

This special edition of the Small Cell SMASHERS features Misty Shields, MD, PhD, as a guest instead of her usual role as host. Dr. Shields is a thoracic medical oncologist, assistant professor of clinical medicine, adjunct assistant professor of medical and molecular genetics, and associate member of experimental and developmental therapeutics at Indiana University School of Medicine and Indiana University Health Physicians. Dr. Shields discusses her American Society of Clinical Oncology (…

Small Cell SMASHERS Fireside Chat with Dr. Trudy Oliver

Small Cell SMASHERS Fireside Chat with Dr. Trudy Oliver

In November, Trudy Oliver, PhD, professor of pharmacology and cancer biology at Duke University School of Medicine and Duke Cancer Institute, discussed the origins of small cell lung cancer (SCLC) and its impact on plasticity.Moderated by Dr. Misty Shields, Indiana University School of Medicine, and LUNGevity’s Ann Fish-Steagall, SVP of Patient Services and Health Care Delivery, this monthly virtual series highlights the latest discoveries and breakthroughs for SCLC.

LUNGevity Foundation Invests $1.2 Million to Fuel Next Generation of Lung Cancer Research

LUNGevity Foundation Invests $1.2 Million to Fuel Next Generation of Lung Cancer Research

LUNGevity Foundation announced $1.2 million in research awards that are designed to strengthen the lung cancer workforce and accelerate progress across the lung cancer continuum—from early detection to treating advanced disease.“Today’s research is tomorrow’s cure. If we want to see continued breakthroughs and advancements in lung cancer, we must secure a strong pipeline of researchers dedicated to improving outcomes for people with lung cancer,” said Upal Basu Roy, PhD, MPH, Executive Director…